screw up

screw up {very informal} ( to make a serious mistake, or to spoil something, especially a situation) — все испортить, облажаться, лажануться; напортачить; ~ наломать дров

...I really screwed up this time, didn't I? (MM)
...I can’t talk to girls, and when I do talk to them, I screw it up. (American Pie)
....Now that I think about it, I realize we really screwed up! If I knew then what I know now, I would have done it differently!
...We’ll be put through the wringer if we screw up again.
...He made a bad decision that screwed up his entire life.

“To screw up” something is to do it very badly.

foul up or foul up the job / works (to do something wrong, or to spoil something, especially by making mistakes)
Just as a coil of rope can get fouled-up when unwinding,
so we may be said to foul-up a job when we make a complete mess of things; mess-up; screw-up the works.

Related vocabulary
[fall flat on one's face]
[put one's foot in it]
[egg on one's face]
goof up
slip up
mess up